Wrist

Carpal Tunnel Syndrome

수근관 증후군

Median nerve compression in the carpal tunnel causing thumb-index-middle finger numbness and thenar muscle weakness

How common
Very common
Typical age
Ages 30–60

What is it?

Elevated carpal tunnel pressure compresses median nerve → sensory-motor dysfunction in median nerve distribution (thumb-index-middle-radial ring finger)

Commonly affected: Median nerve (within carpal tunnel), thenar muscles (opponens pollicis, APB, FPB)

How it develops

  1. Carpal Tunnel AnatomyCarpal tunnel is a narrow channel formed by carpal bones (roof) and transverse carpal ligament (floor) — median nerve and 9 flexor tendons pass through
  2. Pressure IncreaseElevated carpal tunnel pressure (normal 7-8mmHg → >30mmHg in CTS). Flexor tendon thickening, edema, mass, systemic factors
  3. Neural IschemiaPersistent compression reduces intraneural blood flow → neural ischemia → demyelination
  4. Sensorimotor DysfunctionMedian nerve damage → 1st-3rd finger numbness, thenar weakness (in advanced cases)

Symptoms

  • Nocturnal Numbness (Fingers 1-3)Sleep disrupted by thumb-index-middle finger numbness — median nerve distribution
  • Flick SignShaking hand temporarily relieves numbness — highly specific for CTS
  • Thenar WeaknessAdvanced: thenar muscle weakness and atrophy → weak thumb opposition
  • Activity-Related WorseningWorsens with repetitive wrist flexion/extension work, driving, reading

How it is examined

  • Phalen's TestFull wrist flexion with both hands held 60 seconds → reproduces thumb-index-middle finger numbness → Positive (sensitivity 80%)
  • Tinel's Sign (Wrist)Tapping carpal tunnel at wrist → electric shock in 1st-3rd fingers → Positive (high specificity)
  • Thenar Atrophy AssessmentThenar atrophy visible in advanced CTS — APB (abductor pollicis brevis) especially affected
  • Two-Point DiscriminationQuantitative sensory assessment in median nerve distribution — normal ≤5mm

Imaging

Exclude secondary causes such as OA, fracture, or mass

  • Usually normal
  • Identify structures narrowing carpal tunnel
  • Rheumatoid arthritis findings if present

Confirm median nerve compression and evaluate secondary causes (mass, ganglion) — supplements nerve conduction study

  • Median nerve thickening and T2 hyperintensity
  • Carpal tunnel effusion or mass
  • Median nerve flattening

Non-surgical care

  • Wrist Splint (Night)Neutral wrist position splint — most effective when worn at night. Minimizes carpal tunnel pressure
  • Activity ModificationAvoid repetitive wrist flexion/extension, ergonomic keyboard/mouse
  • Steroid InjectionIntracarpal tunnel steroid injection — short-term (3-6 months) effect. Especially useful in pregnancy or mild cases
  • Systemic TreatmentTreat underlying conditions: pregnancy, hypothyroidism, diabetes

Conservative options are generally tried first. Medications listed here can have side effects — discuss them with your prescriber.

When surgery is considered

Failed conservative treatment >3 months, thenar weakness/atrophy, severe nerve conduction abnormalities

Procedures that may be discussed

  • Carpal tunnel release — transverse carpal ligament division. Open or endoscopic
  • Endoscopic surgery has fewer wound complications and faster recovery

Outlook

90-95% symptom improvement after surgery. Thenar atrophy recovers gradually over 1-2 years

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