Ribs / Chest Wall

Tietze Syndrome

티에체 증후군

Costochondritis variant with localized non-suppurative swelling

How common
Uncommon
Typical age
Ages 20–40

What is it?

Non-suppurative inflammation of upper costal cartilage producing focal cartilage thickening and swelling — self-limiting.

Commonly affected: Typically single site — 2nd or 3rd costal cartilage

How it develops

  1. Repetitive Cough/TraumaChronic cough or minor trauma triggers
  2. Perichondral InflammationPerichondrium vasodilation and edema
  3. Cartilage ThickeningVisible focal cartilage enlargement
  4. Gradual ResolutionSwelling recedes over months

Symptoms

  • Tenderness to palpationTender to palpation over swelling
  • Localized swellingVisible cartilage enlargement
  • Anterior chest painPain over swollen area
  • Worse with breathing/motionWorse with deep breath or upper body motion
  • Normal overlying skinNo erythema or warmth — distinguishes from infection

How it is examined

  • Visible swellingFocal prominent cartilage (single site)
  • Fusiform enlargementSpindle-shaped swelling along cartilage
  • Focal tendernessDirect pressure on swelling elicits pain
  • No systemic inflammationNo fever; CRP/ESR usually normal

Imaging

Plain X-ray usually normal; diagnosis is clinical, imaging to exclude alternatives.

  • Normal or mild soft tissue swelling
  • No bony involvement
  • Rule out tumor/infection

MRI shows gadolinium enhancement and edema at affected cartilage; US shows hypoechoic swelling.

  • T2 hyperintensity/edema at cartilage
  • Gadolinium enhancement
  • US: hypoechoic cartilage thickening

Non-surgical care

  • ReassuranceExplain benign self-limiting nature
  • NSAIDsInflammation/pain control for 4–6 weeks
  • Activity modificationAvoid triggers; rest upper body
  • Heat therapyWarm compress for symptom relief

Conservative options are generally tried first. Medications listed here can have side effects — discuss them with your prescriber.

When surgery is considered

Refractory to conservative care

Procedures that may be discussed

  • Local corticosteroid injection
  • Local lidocaine injection

Outlook

Pain resolves in weeks; swelling may persist for months.

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