Urology

Urolithiasis

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Crystalline stones in the urinary tract causing pain and obstruction

How common
Lifetime 10%
Typical age
Men 30–60 most common

What is it?

Urinary supersaturation causes crystal formation, aggregation, and stone growth (mostly calcium oxalate).

Commonly affected: Renal pelvis, ureter, bladder

How it develops

  1. SupersaturationConcentration of Ca/oxalate; dehydration
  2. NucleationCrystal nuclei adhere to mucosa
  3. Stone growthAggregation by further deposition
  4. Ureteral obstructionObstruction at narrow points → renal colic

Symptoms

  • Renal colicCrampy flank pain radiating to groin
  • HematuriaMicroscopic or gross hematuria
  • Nausea/vomitingAccompanies severe pain
  • LUTSFrequency/urgency if near bladder
  • Fever (rare)Indicates infected obstruction; emergency

How it is examined

  • CVA tendernessAffected flank
  • UrinalysisHematuria; pH (acidic in uric acid stones)
  • Stone analysisChemical analysis of passed stone

Imaging

Non-contrast CT (low-dose) is standard; KUB only sees calcium stones.

  • Hyperdense stone
  • Pelvicaliceal dilation
  • Ureteral edema

Renal US in pregnancy to assess hydronephrosis.

  • Hydronephrosis
  • Stone may not be visible

Non-surgical care

  • Hydration + analgesiaNSAIDs (ketorolac) preferred over opioids
  • Medical expulsive therapyTamsulosin 0.4 mg qd aids passage
  • Observation (<5 mm)80% pass spontaneously in 4–6 weeks
  • Stone strainerStrain urine; analyze passed stones
  • Prevention2.5 L/day water, low salt/protein, adequate calcium

Conservative options are generally tried first. Medications listed here can have side effects — discuss them with your prescriber.

When surgery is considered

Stones >5 mm, persistent pain, obstruction, infection

Procedures that may be discussed

  • ESWL (extracorporeal shockwave)
  • Ureteroscopy + holmium laser
  • PCNL (>2 cm stones)

Outlook

50% recur within 5 years; prevention is critical.

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