Obstetrics & Gynecology

Normal Pregnancy

정상임신

Implantation of fertilized ovum in endometrium with fetal development over ~40 weeks

How common
Natural physiologic state in reproductive-age women
Typical age
Ages 15–49

What is it?

Fertilization → implantation → placental formation → hormonal milieu (hCG, progesterone, estrogen) sustains pregnancy.

Commonly affected: Uterus, placenta, fetus, systemic maternal adaptation

How it develops

  1. Fertilization & implantationFertilization in ampulla; implantation 6–10 days post-ovulation
  2. hCG secretionTrophoblast secretes hCG, maintains corpus luteum and progesterone
  3. Placental developmentPlacenta complete by 12 wk; takes over hormones, nutrients, gas exchange
  4. Fetal growth & term37–42 wk term; oxytocin surge initiates labor

Symptoms

  • Nausea/vomiting (morning sickness)Peaks 6–12 weeks
  • FatigueProgesterone-induced sedation
  • AmenorrheaFirst diagnostic clue
  • Breast tenderness/enlargementEstrogen/progesterone effect
  • Urinary frequencyEnlarged uterus compresses bladder

How it is examined

  • Urine/serum β-hCGPositive 8–10 days post-fertilization
  • Transvaginal USGestational sac at 5 wk, fetal cardiac activity at 6 wk
  • Prenatal panelType/Rh, CBC, rubella/HBV/HIV/syphilis, glucose

Imaging

X-ray avoided in pregnancy; US is standard.

  • Gestational sac
  • Fetal heartbeat
  • Placental location

MRI without contrast available if needed; useful for fetal anomaly evaluation.

  • Fetal anatomy
  • Placental attachment

Non-surgical care

  • Folic acid0.4–0.8 mg/day from preconception (NTD prevention)
  • Prenatal visitsQ4w until 28 wk → Q2w until 36 wk → weekly
  • VaccinationsInfluenza (any time), Tdap (27–36 wk), COVID-19
  • LifestyleNo smoking/alcohol, caffeine <200 mg, balanced diet
  • Weight gain11–16 kg for normal BMI per IOM

Conservative options are generally tried first. Medications listed here can have side effects — discuss them with your prescriber.

When surgery is considered

Cesarean only for obstetric indications (malpresentation, previa, fetal distress)

Procedures that may be discussed

  • Vaginal delivery
  • Elective or emergency cesarean section
  • Episiotomy/operative vaginal (forceps/vacuum)

Outlook

Most reach term without complications; maternal/neonatal mortality very low with prenatal care.

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