Cardiology

Atrial Fibrillation

심방세동

Irregular atrial electrical activity; increases stroke risk 5-fold

How common
5% in 60s, 10% in 80s
Typical age
Increases after age 60

What is it?

Ectopic foci near pulmonary vein ostia trigger reentry → chaotic atrial activity → irregular ventricular response → LA stasis → thrombus → embolic stroke.

Commonly affected: Atria, LA appendage, brain (embolic)

How it develops

  1. PV triggerIncreased automaticity at PV ostia
  2. Atrial reentryStructural/electrical remodeling
  3. Irregular ventricular responseIrregular AV node conduction
  4. LA thrombus/strokeLA appendage stasis

Symptoms

  • Stroke (complication)Devastating complication
  • PalpitationsAwareness of irregular heartbeat
  • DizzinessReduced cardiac output
  • DyspneaWith concurrent HF
  • FatigueReduced cardiac output

How it is examined

  • Pulse examIrregularly irregular, often rapid
  • ECG (essential)No P waves, irregular RR, fibrillatory waves
  • CHA2DS2-VASc scoreStroke risk stratification

Imaging

CXR for HF/underlying disease.

  • Possible LA enlargement

TEE to rule out LA appendage thrombus (before cardioversion/ablation).

  • LA enlargement
  • LAA thrombus (possible)

Non-surgical care

  • Rate controlBeta-blocker, CCB (diltiazem), digoxin
  • Rhythm control (selective)Amiodarone, flecainide (selected patients)
  • Anticoagulation (CHA2DS2-VASc based)DOAC (apixaban, rivaroxaban) or warfarin
  • Electrical cardioversionFor instability or severe symptoms

Conservative options are generally tried first. Medications listed here can have side effects — discuss them with your prescriber.

When surgery is considered

Failed medical therapy or severe symptoms

Procedures that may be discussed

  • Pulmonary vein isolation (catheter ablation)
  • Maze procedure (concomitant with heart surgery)
  • LA appendage occlusion (Watchman, if anticoag contraindicated)

Outlook

Anticoagulation reduces stroke risk 60-70%; ablation success rate 70-80%.

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