Neurology

Obstructive Sleep Apnea

폐쇄성수면무호흡

Repetitive upper airway collapse during sleep with hypoxemia

How common
Commonly encountered in neurology
Typical age
Variable age

What is it?

Core pathophysiology of Obstructive Sleep Apnea.

Commonly affected: Affected neural region (peripheral nerve, brain, spinal cord, or muscle)

How it develops

  1. Trigger/predispositionTriggering or predisposing factors for Obstructive Sleep Apnea
  2. Neural injurySpecific nerve/muscle injury occurs
  3. ManifestationCharacteristic neurologic features appear
  4. CourseRecovery or progression depends on treatment

Symptoms

  • Characteristic neurologic symptomClassic Obstructive Sleep Apnea feature
  • Motor/sensory changeWeakness, sensory loss, paresthesia
  • Functional impairmentDifficulty with ADLs

How it is examined

  • Neurologic examStrength, sensation, reflex, cranial nerve, cerebellar
  • Specific testsAppropriate workup for Obstructive Sleep Apnea (NCS/EMG/MRI/serology)

Imaging

Plain X-ray generally not used for diagnosis.

  • N/A

Brain/spine MRI or NCS/EMG as appropriate.

  • Region-specific neurologic findings

Non-surgical care

  • PharmacotherapyDiagnosis-specific neurologic medication
  • Rehab/PTFunctional recovery and maintenance
  • Trigger managementModify identified triggers

Conservative options are generally tried first. Medications listed here can have side effects — discuss them with your prescriber.

When surgery is considered

Refractory or structural abnormality

Procedures that may be discussed

  • Nerve decompression or targeted procedure
  • Immunotherapy/plasmapheresis (if autoimmune)

Outlook

Variable based on timing of diagnosis/treatment; most improve with active care.

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